Smap2 Gene Summary [Mouse]
Predicted to enable GTPase activator activity. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in cytoplasm. Is expressed in several structures, including central nervous system; ganglia; genitourinary system; spleen; and upper jaw. Orthologous to human SMAP2 (small ArfGAP2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Smap2 |
| Official Name | small ArfGAP 2 [Source:MGI Symbol;Acc:MGI:1917030] |
| Ensembl ID | ENSMUSG00000032870 |
| Bio databases IDs | |
| Aliases | small ArfGAP 2 |
| Synonyms | 1810031K02Rik, LOC107984945, RGD1308418, small ArfGAP 2, SMAP1L |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Smap2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Putative GTP-ase activating proteins for the small GTPase, ARF
- protein binding
- GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)
- Putative GTPase activating protein for Arf
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
- trans Golgi network
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Smap2 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- cytosol
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- metal ion binding
- GTPase activator activity