Rpusd4 Gene Summary [Rat]
Predicted to enable mitochondrial ribosomal large subunit rRNA binding activity; pseudouridine synthase activity; and tRNA binding activity. Predicted to be involved in positive regulation of mitochondrial translation and pseudouridine synthesis. Predicted to be located in mitochondrial matrix; nucleoplasm; and ribonucleoprotein granule. Orthologous to human RPUSD4 (RNA pseudouridine synthase D4). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rpusd4 |
| Official Name | RNA pseudouridine synthase D4 [Source:RGD Symbol;Acc:1311268] |
| Ensembl ID | ENSRNOG00000011567 |
| Bio databases IDs | |
| Aliases | RNA pseudouridine synthase D4 |
| Synonyms | 2410001E19Rik, RGD1311268, RNA pseudouridine synthase D4, RNA pseudouridylate synthase domain containing 4 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Rpusd4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- tRNA binding
- PseudoU_synth
- rRNA binding
- pseudouridine synthase, RluA family
- pseudouridine synthase
- enzyme
- protein binding
- RNA pseudouridylate synthase
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- ribonucleoprotein granule
- Mitochondria
- mitochondrial matrix
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Rpusd4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mitochondrial tRNA pseudouridine synthesis
- RNA splicing
- positive regulation of mitochondrial translation
- mRNA processing
- rRNA processing
Cellular Component
Where in the cell the gene product is active
- ribonucleoprotein granule
- mitochondrial matrix
- mitochondrion
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding
- pseudouridine synthase activity
- tRNA binding