Plppr2 Gene Summary [Rat]

Predicted to enable phosphatidate phosphatase activity. Predicted to be involved in phospholipid dephosphorylation; phospholipid metabolic process; and signal transduction. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human PLPPR2 (phospholipid phosphatase related 2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Plppr2
Official Name
phospholipid phosphatase related 2 [Source:RGD Symbol;Acc:1597171]
Ensembl ID
ENSRNOG00000012164
Bio databases IDs NCBI: 300443 Ensembl: ENSRNOG00000012164
Aliases phospholipid phosphatase related 2
Synonyms LPPR2, LPPRP2, phospholipid phosphatase related 2, PRG-4
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Plppr2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Acid phosphatase homologues
  • PAP2 superfamily
  • phosphatidate phosphatase
  • phosphatase
  • protein binding
  • PAP2_like

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • alveolar rhabdomyosarcoma
  • soft tissue sarcoma cancer
  • latent tuberculosis
role in cell
  • survival

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Plppr2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • phospholipid dephosphorylation
  • signal transduction
  • phospholipid metabolic process

Cellular Component

Where in the cell the gene product is active
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • phosphatidate phosphatase activity
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.