Zfyve21 Gene Summary [Rat]

Predicted to enable zinc ion binding activity. Predicted to be located in endosome and focal adhesion. Orthologous to human ZFYVE21 (zinc finger FYVE-type containing 21). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Zfyve21
Official Name
zinc finger FYVE-type containing 21 [Source:RGD Symbol;Acc:1311036]
Ensembl ID
ENSRNOG00000012185
Bio databases IDs NCBI: 362789 Ensembl: ENSRNOG00000012185
Aliases zinc finger FYVE-type containing 21
Synonyms 1110013H04RIK, HCVP7TP1, ZF21, zinc finger, FYVE domain containing 21, zinc finger FYVE-type containing 21
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Zfyve21 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • FYVE domain like superfamily
  • FYVE zinc finger
  • Zinc finger FYVE domain-containing protein 21 C-terminus
  • Protein present in Fab1, YOTB, Vac1, and EEA1
  • PHD finger superfamily
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • metastasis
regulated by
  • Immunoglobulin
  • KLF3
regulates
  • focal adhesion kinase
role in cell
  • migration
  • invasion
  • disassembly
  • disassembly in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Zfyve21 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • endosome
  • focal adhesion

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • metal ion binding

Gene-Specific Assays for Results You Can Trust

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