Zfyve21 Gene Summary [Mouse]
Predicted to enable zinc ion binding activity. Predicted to be located in endosome and focal adhesion. Is expressed in several structures, including brain; cardiovascular system; genitourinary system; gut; and liver and biliary system. Orthologous to human ZFYVE21 (zinc finger FYVE-type containing 21). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Zfyve21 |
| Official Name | zinc finger, FYVE domain containing 21 [Source:MGI Symbol;Acc:MGI:1915770] |
| Ensembl ID | ENSMUSG00000021286 |
| Bio databases IDs | |
| Aliases | zinc finger, FYVE domain containing 21 |
| Synonyms | 1110013H04RIK, HCVP7TP1, ZF21, zinc finger, FYVE domain containing 21, zinc finger FYVE-type containing 21 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Zfyve21 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- FYVE domain like superfamily
- FYVE zinc finger
- Zinc finger FYVE domain-containing protein 21 C-terminus
- Protein present in Fab1, YOTB, Vac1, and EEA1
- PHD finger superfamily
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Zfyve21 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- endosome
- focal adhesion
Molecular Function
What the gene product does at the molecular level
- protein binding
- metal ion binding