ZFYVE21 Gene Summary [Human]

Predicted to enable metal ion binding activity. Predicted to be located in endosome and focal adhesion. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
ZFYVE21
Official Name
zinc finger FYVE-type containing 21 [Source:HGNC Symbol;Acc:HGNC:20760]
Ensembl ID
ENSG00000100711
Bio databases IDs NCBI: 79038 Ensembl: ENSG00000100711
Aliases zinc finger FYVE-type containing 21
Synonyms 1110013H04RIK, HCVP7TP1, ZF21, zinc finger, FYVE domain containing 21, zinc finger FYVE-type containing 21
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ZFYVE21 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • FYVE domain like superfamily
  • FYVE zinc finger
  • Zinc finger FYVE domain-containing protein 21 C-terminus
  • Protein present in Fab1, YOTB, Vac1, and EEA1
  • PHD finger superfamily
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • metastasis
regulated by
  • Immunoglobulin
  • KLF3
regulates
  • focal adhesion kinase
role in cell
  • migration
  • invasion
  • disassembly
  • disassembly in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human ZFYVE21 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • endosome
  • focal adhesion

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • metal ion binding

Gene-Specific Assays for Results You Can Trust

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