Khdrbs2 Gene Summary [Rat]
Predicted to enable RNA binding activity and protein domain specific binding activity. Predicted to be involved in regulation of alternative mRNA splicing, via spliceosome. Predicted to be active in nucleus. Orthologous to human KHDRBS2 (KH RNA binding domain containing, signal transduction associated 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Khdrbs2 |
| Official Name | KH RNA binding domain containing, signal transduction associated 2 [Source:RGD Symbol;Acc:621738] |
| Ensembl ID | ENSRNOG00000012284 |
| Bio databases IDs | |
| Aliases | KH RNA binding domain containing, signal transduction associated 2 |
| Synonyms | 6330586C16Rik, KH domain containing, RNA binding, signal transduction associated 2, KHDRBS2-OT, KHDRBS2-OT1, KH RNA binding domain containing, signal transduction associated 2, mSLM-1, RP1 240B83, Slim1, SLM-1, Tg(LRRK2*R1441G)135Cjli, TG-RP135 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Khdrbs2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Qua1 domain
- K homology (KH) RNA-binding domain, type I
- SH2-domain binding
- poly(A) binding protein
- protein binding
- Tyrosine-rich domain of Sam68
- SH3-domain binding
- poly(U) binding protein
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
- nuclear bodies
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Khdrbs2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of alternative nuclear mRNA splicing, via spliceosome
- mRNA processing
Cellular Component
Where in the cell the gene product is active
- nucleus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- poly(A) RNA binding
- mRNA binding
- poly(U) RNA binding
- SH3 domain binding
- SH2 domain binding