Larp6 Gene Summary [Rat]

Predicted to enable RNA binding activity and myosin binding activity. Predicted to be involved in positive regulation of collagen biosynthetic process. Predicted to be located in cytoplasm. Predicted to be part of ribonucleoprotein complex. Predicted to be active in nucleus. Orthologous to human LARP6 (La ribonucleoprotein 6, translational regulator). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Larp6
Official Name
La ribonucleoprotein 6, translational regulator [Source:RGD Symbol;Acc:1308414]
Ensembl ID
ENSRNOG00000012438
Bio databases IDs NCBI: 315731 Ensembl: ENSRNOG00000012438
Aliases La ribonucleoprotein 6, translational regulator
Synonyms 5430431G03Rik, ACHN, La ribonucleoprotein 6, translational regulator, RGD1308414
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Larp6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • myosin binding
  • RNA recognition motif (RRM) superfamily
  • La domain
  • mRNA 5' UTR binding
  • RNA recognition motif
  • mRNA binding
  • protein binding
  • LA motif RNA-binding domain
  • RNA binding
  • SUZ-C motif

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • hepatic fibrosis
  • obesity
  • myocardial fibrosis
  • pulmonary fibrosis
regulated by
  • beta-estradiol
  • IGF1
  • TGF beta
  • cycloheximide
  • diethylstilbestrol
  • NORAD
regulates
  • Collagen(s)

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Nucleus

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Larp6 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • regulation of translation
  • positive regulation of collagen biosynthetic process
  • RNA processing

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • mRNA 5'-UTR binding
  • RNA stem-loop binding
  • myosin binding
  • mRNA binding

Gene-Specific Assays for Results You Can Trust

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