Tsn Gene Summary [Rat]
Contributes to sequence-specific DNA binding activity and single-stranded DNA binding activity. Predicted to be involved in siRNA processing. Predicted to be located in endoplasmic reticulum; male germ cell nucleus; and nucleoplasm. Predicted to be part of endoribonuclease complex. Predicted to be active in cytoplasm and nucleus. Orthologous to human TSN (translin). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tsn |
| Official Name | translin [Source:RGD Symbol;Acc:621107] |
| Ensembl ID | ENSRNOG00000002319 |
| Bio databases IDs | |
| Aliases | translin |
| Synonyms | 2610034C24Rik, BCLF-1, C3PO, RCHF1, REHF-1, TB-RBP, translin, TRSLN |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Tsn often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- nuclear export signal
- Translin and translin-associated factor-X (TRAX)
- mRNA binding
- oligomerization domain
- protein binding
- sequence-specific DNA binding
- identical protein binding
- DNA binding
- RNA binding
- Translin family
- binding protein
- single-stranded DNA binding
- basic domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- perinuclear region
- Endoplasmic Reticulum
- cytosol
- nucleoplasm
- chromatin
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Tsn gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- posttranscriptional gene silencing by RNA
- DNA recombination
- production of siRNA involved in RNA interference
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- cytosol
- endoplasmic reticulum
- male germ cell nucleus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- DNA binding
- identical protein binding
- RNA binding
- protein binding
- endonuclease activity
- mRNA binding
- sequence-specific DNA binding
- single-stranded DNA binding