Kcnv2 Gene Summary [Rat]
Predicted to enable potassium channel regulator activity. Predicted to be involved in action potential and potassium ion transmembrane transport. Predicted to be part of voltage-gated potassium channel complex. Predicted to be active in membrane. Human ortholog(s) of this gene implicated in retinal cone dystrophy 3B. Orthologous to human KCNV2 (potassium voltage-gated channel modifier subfamily V member 2). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Kcnv2 |
| Official Name | potassium voltage-gated channel modifier subfamily V member 2 [Source:RGD Symbol;Acc:1309271] |
| Ensembl ID | ENSRNOG00000012566 |
| Bio databases IDs | |
| Aliases | potassium voltage-gated channel modifier subfamily V member 2 |
| Synonyms | KV11.1, Kv8.2, potassium channel, subfamily V, member 2, potassium voltage-gated channel modifier subfamily V member 2, RCD3B |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Kcnv2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- NAB domain
- Ion transport protein
- Broad-Complex, Tramtrack and Bric a brac
- BTB_POZ
- protein binding
- ion channel
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- non-insulin-dependent diabetes mellitus
- retinal dystrophy
- retinal cone dystrophy 3
- cone dystrophy
- retinal cone dystrophy 3B
- fundus flavimaculatus
- progressive cone dystrophy without rod involvement
role in cell
- abnormal morphology
- number
- electrophysiology
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
- Endoplasmic Reticulum
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Kcnv2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- potassium ion transmembrane transport
- protein homooligomerization
- regulation of action potential
Cellular Component
Where in the cell the gene product is active
- voltage-gated potassium channel complex
- membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- voltage-gated potassium channel activity
- protein binding