Pdzk1ip1 Gene Summary [Rat]
Predicted to be located in apical plasma membrane. Orthologous to human PDZK1IP1 (PDZK1 interacting protein 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Pdzk1ip1 |
| Official Name | PDZK1 interacting protein 1 [Source:RGD Symbol;Acc:620952] |
| Ensembl ID | ENSRNOG00000008161 |
| Bio databases IDs | |
| Aliases | PDZK1 interacting protein 1 |
| Synonyms | 0610007F13Rik, 2700030M23Rik, DD96, MAP17, PDZK1 interacting protein 1, SPAP |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Pdzk1ip1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- Membrane-associated protein 117 kDa, PDZK1-interacting protein 1
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- metastasis
- breast cancer
- colorectal cancer
- Klinefelter syndrome
- Turner syndrome
- plaque psoriasis
- psoriasis
- Wilms tumor
- Wilms tumorigenesis
- thyroid carcinoma
role in cell
- proliferation
- migration
- epithelial-mesenchymal transition
- senescence
- transcription in
- tumorigenicity
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- cellular membrane
- cell-cell contacts
- cytoplasmic face of plasma membrane
- apical membrane
- brush border
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Pdzk1ip1 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
- membrane
Molecular Function
What the gene product does at the molecular level
- protein binding