Dpp7 Gene Summary [Rat]
Enables dipeptidyl-peptidase activity. Involved in protein catabolic process. Predicted to be located in Golgi apparatus and lysosome. Predicted to be active in vesicle. Orthologous to human DPP7 (dipeptidyl peptidase 7). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Dpp7 |
| Official Name | dipeptidylpeptidase 7 [Source:RGD Symbol;Acc:71073] |
| Ensembl ID | ENSRNOG00000012640 |
| Bio databases IDs | |
| Aliases | dipeptidylpeptidase 7 |
| Synonyms | dipeptidase7, dipeptidyl peptidase 7, DPP2, DPPII, EST110582, QPP, QUIESCENT CELL PROLINE DIPEPTIDASE |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Dpp7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- serine-type peptidase
- alpha/beta hydrolases
- peptidase
- dipeptidyl-peptidase II
- Serine carboxypeptidase S28
- dipeptidyl-peptidase
Pathways
Biological processes and signaling networks where the Dpp7 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- insulin resistance
- impaired glucose tolerance
- Alzheimer disease
- gastroesophageal reflux
- hyperinsulinism
- papillary thyroid carcinoma
- papillary thyroid cancer
- hepatic steatosis
regulates
- lipid
role in cell
- apoptosis
- quiescence
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- lysosome fractions
- intracellular membrane-bounded organelle
- azurophil granule lumen
- Extracellular Space
- vesicles
- lysosome
- Golgi Apparatus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Dpp7 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- proteolysis
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
- intracellular membrane-bounded organelle
- vesicle
- Golgi apparatus
- extracellular region
- azurophil granule lumen
Molecular Function
What the gene product does at the molecular level
- serine-type peptidase activity
- aminopeptidase activity
- dipeptidyl-peptidase activity
- serine-type exopeptidase activity