Cklf Gene Summary [Rat]
Predicted to enable chemokine activity. Involved in neutrophil chemotaxis. Predicted to be located in extracellular region. Predicted to be active in membrane. Orthologous to human CKLF (chemokine like factor). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cklf |
| Official Name | chemokine-like factor [Source:RGD Symbol;Acc:620708] |
| Ensembl ID | ENSRNOG00000012752 |
| Bio databases IDs | |
| Aliases | chemokine-like factor |
| Synonyms | 1700001C14RIK, C32, chemokine-like factor, Chemokine-like factor 1, CKLF1, HSPC224, UCK-1 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cklf often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Membrane-associating domain
- chemokine
- protein binding
- cytokine
Pathways
Biological processes and signaling networks where the Cklf gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Cklf gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- lymphocyte chemotaxis
- macrophage chemotaxis
- signal transduction
- neutrophil chemotaxis
- secretion by cell
Cellular Component
Where in the cell the gene product is active
- extracellular space
- membrane
- extracellular region
Molecular Function
What the gene product does at the molecular level
- protein binding
- chemokine activity