Minar1 Gene Summary [Rat]
Involved in negative regulation of TOR signaling; negative regulation of neuron projection development; and negative regulation of protein ubiquitination. Predicted to be located in endomembrane system. Predicted to be active in plasma membrane. Orthologous to human MINAR1 (membrane integral NOTCH2 associated receptor 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Minar1 |
| Official Name | membrane integral NOTCH2 associated receptor 1 [Source:RGD Symbol;Acc:1591930] |
| Ensembl ID | ENSRNOG00000013399 |
| Bio databases IDs | |
| Aliases | membrane integral NOTCH2 associated receptor 1 |
| Synonyms | AF529169, DD1, KIAA1024, membrane integral NOTCH2 associated receptor 1, UBTOR |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Minar1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- MINAR1 C-terminal domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Minar1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of angiogenesis
- negative regulation of neuron projection development
- negative regulation of cell growth
- angiogenesis
- negative regulation of cell proliferation
- negative regulation of protein ubiquitination
- negative regulation of TOR signaling cascade
Cellular Component
Where in the cell the gene product is active
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding