MINAR1 Gene Summary [Human]
Involved in several processes, including negative regulation of TOR signaling; negative regulation of angiogenesis; and negative regulation of protein ubiquitination. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | MINAR1 |
| Official Name | membrane integral NOTCH2 associated receptor 1 [Source:HGNC Symbol;Acc:HGNC:29172] |
| Ensembl ID | ENSG00000169330 |
| Bio databases IDs | |
| Aliases | membrane integral NOTCH2 associated receptor 1, major intrinsically disordered Notch2-associated receptor 1 |
| Synonyms | AF529169, DD1, KIAA1024, membrane integral NOTCH2 associated receptor 1, UBTOR |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MINAR1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- MINAR1 C-terminal domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human MINAR1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of angiogenesis
- negative regulation of neuron projection development
- negative regulation of cell growth
- angiogenesis
- negative regulation of cell proliferation
- negative regulation of protein ubiquitination
- negative regulation of TOR signaling cascade
Cellular Component
Where in the cell the gene product is active
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding