Pdcd7 Gene Summary [Rat]
Predicted to be involved in response to glucocorticoid. Predicted to act upstream of or within RNA splicing; positive regulation of T cell apoptotic process; and positive regulation of apoptotic signaling pathway. Predicted to be part of U12-type spliceosomal complex and U2AF complex. Orthologous to human PDCD7 (programmed cell death 7). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Pdcd7 |
| Official Name | programmed cell death 7 [Source:RGD Symbol;Acc:1308961] |
| Ensembl ID | ENSRNOG00000014340 |
| Bio databases IDs | |
| Aliases | programmed cell death 7 |
| Synonyms | 59K, ES18, HES18, programmed cell death 7 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Pdcd7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Programmed cell death protein 7
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- spliceosomes
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Pdcd7 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- RNA splicing
- response to glucocorticoid stimulus
- apoptotic process
Cellular Component
Where in the cell the gene product is active
- U12-type spliceosomal complex
- nucleoplasm