PDCD7 Gene Summary [Human]
This gene encodes a 59 kDa protein that is associated with the U11 small nuclear ribonucleoprotein (snRNP), which is a component of the minor U12-type spliceosome responsible for catalyzing pre-mRNA splicing of U12-type introns. [provided by RefSeq, Dec 2010]
Details
| Type | Protein Coding |
| Official Symbol | PDCD7 |
| Official Name | programmed cell death 7 [Source:HGNC Symbol;Acc:HGNC:8767] |
| Ensembl ID | ENSG00000090470 |
| Bio databases IDs | |
| Aliases | programmed cell death 7, U11/U12 snRNP 59K |
| Synonyms | 59K, ES18, HES18, programmed cell death 7 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PDCD7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Programmed cell death protein 7
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- spliceosomes
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human PDCD7 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- RNA splicing
- response to glucocorticoid stimulus
- apoptotic process
Cellular Component
Where in the cell the gene product is active
- U12-type spliceosomal complex
- nucleoplasm