Ltv1 Gene Summary [Rat]

Predicted to be involved in ribosomal small subunit biogenesis and ribosomal small subunit export from nucleus. Predicted to be located in nucleoplasm. Predicted to be part of preribosome, small subunit precursor. Predicted to be active in cytosol and nucleus. Human ortholog(s) of this gene implicated in inflammatory poikiloderma with hair abnormalities and acral keratoses. Orthologous to human LTV1 (LTV1 ribosome biogenesis factor). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Ltv1
Official Name
LTV1 ribosome biogenesis factor [Source:RGD Symbol;Acc:1311264]
Ensembl ID
ENSRNOG00000015217
Bio databases IDs NCBI: 361452 Ensembl: ENSRNOG00000015217
Aliases LTV1 ribosome biogenesis factor
Synonyms 2610020N02Rik, C6orf93, dJ468K18.4, IPHAK, LTV1 ribosome biogenesis factor, RGD1311264
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ltv1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Low temperature viability protein
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • inflammatory poikiloderma with hair abnormalities and acral keratoses
regulated by
role in cell
  • apoptosis
  • processing in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • cytosol
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Ltv1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • ribosomal small subunit export from nucleus
  • ribosomal small subunit biogenesis
  • ribosome biogenesis

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytosol
  • preribosome, small subunit precursor
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.