Tent5c Gene Summary [Rat]
Enables RNA adenylyltransferase activity. Involved in mRNA stabilization. Located in cytoplasm and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | Tent5c |
| Official Name | terminal nucleotidyltransferase 5C [Source:RGD Symbol;Acc:1359446] |
| Ensembl ID | ENSRNOG00000015222 |
| Bio databases IDs | |
| Aliases | terminal nucleotidyltransferase 5C |
| Synonyms | 4930431B09Rik, FAM46C, terminal nucleotidyltransferase 5C |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Tent5c often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- nucleotidyltransferase
- enzyme
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- non-insulin-dependent diabetes mellitus
- diabetes mellitus
- X-linked immunodeficiency with magnesium defect, Epstein-Barr virus infection and neoplasia
- cataract
- paroxysmal nocturnal hemoglobinuria
- doxorubicin induced cardiotoxicity
- plasma cell myeloma
- diabetic neuropathy
role in cell
- apoptosis
- accumulation in
- differentiation
- autophagy in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- Cytoplasm
- Nucleus
- centrosome
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Tent5c gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- in utero embryonic development
- negative regulation of cell differentiation
- mRNA stabilization
Cellular Component
Where in the cell the gene product is active
- nucleus
- centrosome
- cytoplasm
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding