Klhl14 Gene Summary [Rat]

Predicted to be located in actin cytoskeleton; aggresome; and cytosol. Predicted to be active in endoplasmic reticulum; neuron projection; and neuronal cell body. Orthologous to human KLHL14 (kelch like family member 14). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Klhl14
Official Name
kelch-like family member 14 [Source:RGD Symbol;Acc:1566178]
Ensembl ID
ENSRNOG00000015418
Bio databases IDs NCBI: 364823 Ensembl: ENSRNOG00000015418
Aliases kelch-like family member 14
Synonyms 6330403N15Rik, kelch-like 14, kelch-like family member 14, printor, RGD1566178
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Klhl14 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Galactose oxidase, central domain
  • Kelch motif
  • BTB And C-terminal Kelch
  • Broad-Complex, Tramtrack and Bric a brac
  • BTB_POZ
  • BTB/POZ domain
  • protein binding
  • BACK (BTB and C-terminal Kelch) domain
  • Kelch domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
  • IFN beta
  • birabresib
  • PTF1A

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • aggresome
  • actin cytoskeleton
  • Endoplasmic Reticulum
  • cytosol
  • neurites
  • perikaryon

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Klhl14 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • endoplasmic reticulum membrane
  • cytoplasm
  • actin cytoskeleton
  • cytosol
  • endoplasmic reticulum
  • neuronal cell body
  • aggresome
  • neuron projection

Gene-Specific Assays for Results You Can Trust

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