Klhl14 Gene Summary [Mouse]

Located in neuron projection and neuronal cell body. Is expressed in several structures, including central nervous system; endocrine gland; metanephros; sensory organ; and thymus primordium. Orthologous to human KLHL14 (kelch like family member 14). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Klhl14
Official Name
kelch-like 14 [Source:MGI Symbol;Acc:MGI:1921249]
Ensembl ID
ENSMUSG00000042514
Bio databases IDs NCBI: 225266 Ensembl: ENSMUSG00000042514
Aliases kelch-like 14
Synonyms 6330403N15Rik, kelch-like 14, kelch-like family member 14, printor, RGD1566178
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Klhl14 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Galactose oxidase, central domain
  • Kelch motif
  • BTB And C-terminal Kelch
  • Broad-Complex, Tramtrack and Bric a brac
  • BTB_POZ
  • BTB/POZ domain
  • protein binding
  • BACK (BTB and C-terminal Kelch) domain
  • Kelch domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
  • IFN beta
  • birabresib
  • PTF1A

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • aggresome
  • actin cytoskeleton
  • Endoplasmic Reticulum
  • cytosol
  • neurites
  • perikaryon

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Klhl14 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • endoplasmic reticulum membrane
  • cytoplasm
  • actin cytoskeleton
  • cytosol
  • endoplasmic reticulum
  • neuronal cell body
  • aggresome
  • neuron projection

Gene-Specific Assays for Results You Can Trust

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