Elmo3 Gene Summary [Rat]
Predicted to enable SH3 domain binding activity. Predicted to be involved in actin filament organization and cell motility. Predicted to be located in cytoplasm. Orthologous to human ELMO3 (engulfment and cell motility 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Elmo3 |
| Official Name | engulfment and cell motility 3 [Source:RGD Symbol;Acc:1304734] |
| Ensembl ID | ENSRNOG00000015800 |
| Bio databases IDs | |
| Aliases | engulfment and cell motility 3 |
| Synonyms | 9930107J06, CED-12, engulfment and cell motility 3 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Elmo3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ELMO, armadillo-like helical domain
- ELMO/CED-12 family
- protein binding
- Pleckstrin homology-like domain
- Pleckstrin homology domain
Pathways
Biological processes and signaling networks where the Elmo3 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Elmo3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell motility
- apoptotic process
- phagocytosis
- actin filament organization
Cellular Component
Where in the cell the gene product is active
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- SH3 domain binding