Fxyd6 Gene Summary [Rat]
This gene encodes a member of the FXYD family of transmembrane proteins. This particular protein encodes phosphohippolin, which likely affects the activity of Na,K-ATPase. Multiple alternatively spliced transcript variants encoding the same protein have been described. Related pseudogenes have been identified on chromosomes 10 and X. Read-through transcripts have been observed between this locus and the downstream sodium/potassium-transporting ATPase subunit gamma (FXYD2, GeneID 486) locus.[provided by RefSeq, Feb 2011]
Details
| Type | Protein Coding |
| Official Symbol | Fxyd6 |
| Official Name | FXYD domain-containing ion transport regulator 6 [Source:RGD Symbol;Acc:69315] |
| Ensembl ID | ENSRNOG00000016412 |
| Bio databases IDs | |
| Aliases | FXYD domain-containing ion transport regulator 6 |
| Synonyms | 0610030I18Rik, FXYD domain-containing ion transport regulator 6, Php |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Fxyd6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ATP1G1/PLM/MAT8 family
- protein binding
- phenylalanine-X-tyrosine-aspartate (FXYD) family
- ion channel
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- glutaminergic synapse
- cellular membrane
- presynaptic membrane
- postsynaptic membrane
- perikaryon
- dendrites
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Fxyd6 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- potassium ion transport
- sodium ion transport
- regulation of sodium ion transmembrane transporter activity
- regulation of ion transport
Cellular Component
Where in the cell the gene product is active
- presynaptic membrane
- postsynaptic membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- sodium channel regulator activity
- protein binding