Eif3j Gene Summary [Rat]
Predicted to enable identical protein binding activity. Predicted to be involved in formation of cytoplasmic translation initiation complex. Predicted to be located in cytosol. Predicted to be part of eukaryotic translation initiation factor 3 complex. Orthologous to human EIF3J (eukaryotic translation initiation factor 3 subunit J). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Eif3j |
| Official Name | eukaryotic translation initiation factor 3, subunit J [Source:RGD Symbol;Acc:1593338] |
| Ensembl ID | ENSRNOG00000016459 |
| Bio databases IDs | |
| Aliases | eukaryotic translation initiation factor 3, subunit J |
| Synonyms | 1810016I04Rik, 2700079K05Rik, eIF3-alpha, eIF-3-alpha-A, eIF-3-alpha-B, Eif3j1, Eif3j-2, eIF3j-A, eIF3j-B, eIF3-p35, EIF3S1, Eif3s1 (predicted), eIF3-α, eIF-3-α-A, eIF-3-α-B, eukaryotic translation initiation factor 3 subunit J, eukaryotic translation initiation factor 3, subunit J, eukaryotic translation initiation factor 3, subunit J1 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Eif3j often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Translation initiation factor eIF3 subunit
- protein binding
- identical protein binding
- translation regulator
Pathways
Biological processes and signaling networks where the Eif3j gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- androgenic alopecia
- aortic valve calcification
role in cell
- expression in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Eif3j gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- formation of translation initiation complex
- translational initiation
Cellular Component
Where in the cell the gene product is active
- eukaryotic 43S preinitiation complex
- cytosol
- eukaryotic 48S preinitiation complex
- eukaryotic translation initiation factor 3 complex
Molecular Function
What the gene product does at the molecular level
- translation initiation factor activity
- identical protein binding
- protein binding