LOC687679 Gene Summary [Rat]
Enables U1 snRNP binding activity. Predicted to be involved in spliceosomal snRNP assembly. Part of U1 snRNP. Orthologous to human SNRPG (small nuclear ribonucleoprotein polypeptide G). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | LOC687679 |
| Official Name | similar to small nuclear ribonucleoprotein polypeptide G [Source:RGD Symbol;Acc:1583028] |
| Ensembl ID | ENSRNOG00000016507 |
| Bio databases IDs | |
| Aliases | similar to small nuclear ribonucleoprotein polypeptide G |
| Synonyms | 2810024K17Rik, AL022803, D15Mgi25, LOC686174, small nuclear ribonucleoprotein polypeptide G, SMG, snRNP-G |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Loc687679 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Sm and related proteins
- ribonucleoprotein binding
- protein binding
Pathways
Biological processes and signaling networks where the Loc687679 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- peripheral arterial disease
- non-small cell lung cancer
- chronic kidney disease
- renal cell carcinoma
- renal cell cancer
role in cell
- cell viability
- apoptosis
- cell death
- splicing by
- alternative splicing in
- maturation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nuclear fraction
- catalytic step 2 spliceosome
- cytosol
- spliceosomes
- nucleoplasm
- interchromatin granule clusters
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Loc687679 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- RNA splicing
- spliceosomal complex assembly
- nuclear mRNA splicing, via spliceosome
- spliceosomal snRNP assembly
Cellular Component
Where in the cell the gene product is active
- U5 snRNP
- spliceosomal complex
- U2-type spliceosomal complex
- U7 snRNP
- U2 snRNP
- U1 snRNP
- nucleoplasm
- U4 snRNP
- U12-type spliceosomal complex
- nucleus
- catalytic step 2 spliceosome
- methylosome
- precatalytic spliceosome
- U4/U6 x U5 tri-snRNP complex
- P granule
- SMN-Sm protein complex
- cytosol
- U2-type catalytic step 2 spliceosome
- U2-type prespliceosome
- U2-type precatalytic spliceosome
- small nuclear ribonucleoprotein complex
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding