Pllp Gene Summary [Rat]

Predicted to be a structural constituent of myelin sheath. Predicted to be involved in myelination. Predicted to be located in compact myelin and membrane raft. Predicted to be integral component of membrane. Biomarker of schizophrenia. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
Pllp
Official Name
plasmolipin [Source:RGD Symbol;Acc:621478]
Ensembl ID
ENSRNOG00000016558
Bio databases IDs NCBI: 64364 Ensembl: ENSRNOG00000016558
Aliases plasmolipin
Synonyms 0610010I06Rik, Plapi, plasma membrane proteolipid, plasmolipin, PMLP, TM4SF11
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Pllp often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Membrane-associating domain
  • protein binding
  • identical protein binding
  • transporter

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • aortic valve calcification
  • uterine serous papillary cancer
regulated by
regulates
  • ion
role in cell
  • assembly

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cellular membrane
  • apical membrane
  • myelin sheath
  • membrane rafts

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Pllp gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • ion transmembrane transport
  • myelination

Cellular Component

Where in the cell the gene product is active
  • compact myelin
  • membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • structural constituent of myelin sheath

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.