Pllp Gene Summary [Mouse]
Predicted to be a structural constituent of myelin sheath. Predicted to be involved in monoatomic ion transport and myelination. Predicted to act upstream of or within regulation of endocytosis. Predicted to be located in compact myelin. Predicted to be active in membrane. Is expressed in midgut; olfactory epithelium; and stomach. Orthologous to human PLLP (plasmolipin). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Pllp |
| Official Name | plasma membrane proteolipid [Source:MGI Symbol;Acc:MGI:1915051] |
| Ensembl ID | ENSMUSG00000031775 |
| Bio databases IDs | |
| Aliases | plasma membrane proteolipid |
| Synonyms | 0610010I06Rik, Plapi, plasma membrane proteolipid, plasmolipin, PMLP, TM4SF11 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Pllp often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Membrane-associating domain
- protein binding
- identical protein binding
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
- apical membrane
- myelin sheath
- membrane rafts
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Pllp gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- ion transmembrane transport
- myelination
Cellular Component
Where in the cell the gene product is active
- compact myelin
- membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- structural constituent of myelin sheath