Ccnt2 Gene Summary [Rat]
Predicted to enable several functions, including 7SK snRNA binding activity; cyclin-dependent protein serine/threonine kinase activator activity; and enzyme binding activity. Predicted to be involved in several processes, including early viral transcription; late viral transcription; and positive regulation of transcription elongation by RNA polymerase II. Predicted to be located in perinuclear region of cytoplasm. Predicted to be part of cyclin/CDK positive transcription elongation factor complex. Predicted to be active in nucleus. Orthologous to human CCNT2 (cyclin T2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ccnt2 |
| Official Name | cyclin T2 [Source:RGD Symbol;Acc:1309205] |
| Ensembl ID | ENSRNOG00000017113 |
| Bio databases IDs | |
| Aliases | cyclin T2 |
| Synonyms | 2900041I18Rik, Cyclin T2, CYCT2, CycT2a, CycT2b, P-FEBb |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ccnt2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- snRNA binding
- transcription regulator
- protein kinase binding
- Cyclin box fold superfamily
- enzyme binding
- transcription factor binding
- chromatin binding
- Cyclin, N-terminal domain
- protein binding
- domain present in cyclins, TFIIB and Retinoblastoma
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- chronic lymphocytic leukemia
role in cell
- expression in
- differentiation
- mineralization
- signaling in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nuclear fraction
- perinuclear region
- Plasma Membrane
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Ccnt2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell division
- immediate early viral mRNA transcription
- late viral mRNA transcription
- skeletal muscle tissue development
- transcription from RNA polymerase II promoter
- positive regulation of transcription from RNA polymerase II promoter
- positive regulation of transcription elongation, DNA-dependent
- regulation of transcription from RNA polymerase II promoter
- regulation of cyclin-dependent protein kinase activity
Cellular Component
Where in the cell the gene product is active
- nucleus
- perinuclear region of cytoplasm
- cytosol
- positive transcription elongation factor complex b
- plasma membrane
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- RNA polymerase binding
- protein binding
- chromatin binding
- transcription coactivator binding