Nsrp1 Gene Summary [Rat]
Enables mRNA binding activity. Involved in developmental process and regulation of alternative mRNA splicing, via spliceosome. Located in nuclear speck. Part of ribonucleoprotein complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | Nsrp1 |
| Official Name | nuclear speckle splicing regulatory protein 1 [Source:RGD Symbol;Acc:1309863] |
| Ensembl ID | ENSRNOG00000022502 |
| Bio databases IDs | |
| Aliases | nuclear speckle splicing regulatory protein 1 |
| Synonyms | 8030451K07, CCDC55, HSPC095, NEDSSBA, NSpr70, NSrp70, nuclear speckle regulatory protein 1, nuclear speckle splicing regulatory protein 1, RGD1309863 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Nsrp1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- mRNA binding
- Nuclear speckle splicing regulatory protein 1, N-terminal
- protein binding
- Nuclear speckle splicing regulatory protein 1, RS-like domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neurodevelopmental disorder with spasticity, seizures, and brain abnormalities
- metastasis
- organismal death
role in cell
- phosphorylation in
- degradation in
- expression in
- migration
- invasion by
- alternative splicing by
- alternative splicing in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
- nuclear speckles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Nsrp1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- RNA splicing
- in utero embryonic development
- regulation of alternative nuclear mRNA splicing, via spliceosome
- mRNA processing
- developmental process
Cellular Component
Where in the cell the gene product is active
- nucleus
- nuclear speck
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding
- mRNA binding