Bphl Gene Summary [Rat]
Predicted to enable alpha-amino-acid esterase activity and poly(ADP-ribose) glycohydrolase activity. Predicted to be involved in ATP generation from poly-ADP-D-ribose. Predicted to be located in cytosol; mitochondrion; and nuclear body. Orthologous to human BPHL (biphenyl hydrolase like). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Bphl |
| Official Name | biphenyl hydrolase like [Source:RGD Symbol;Acc:1307572] |
| Ensembl ID | ENSRNOG00000017577 |
| Bio databases IDs | |
| Aliases | biphenyl hydrolase like |
| Synonyms | 2010012D11RIK, AI115341, biphenyl hydrolase like, Biphenyl Hydrolase Related, BPH-RP, MCNAA, VACVASE |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Bphl often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- alpha/beta hydrolase fold
- poly(ADp-ribose) glycohydrolase
- alpha/beta hydrolases
- Alpha/beta hydrolase family
- Serine aminopeptidase, S33
- serine hydrolase
- alpha-amino-acid esterase
- enzyme
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- Mitochondria
- cytosol
- mitochondrial outer membrane
- nucleoplasm
- nuclear bodies
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Bphl gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- xenobiotic metabolic process
- cellular amino acid metabolic process
- response to toxin
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- mitochondrial outer membrane
Molecular Function
What the gene product does at the molecular level
- alpha-amino-acid esterase activity