Phf23 Gene Summary [Rat]
Predicted to enable zinc ion binding activity. Predicted to be involved in negative regulation of autophagosome assembly; negative regulation of autophagosome maturation; and positive regulation of protein ubiquitination. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Orthologous to human PHF23 (PHD finger protein 23). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Phf23 |
| Official Name | PHD finger protein 23 [Source:RGD Symbol;Acc:1302969] |
| Ensembl ID | ENSRNOG00000017657 |
| Bio databases IDs | |
| Aliases | PHD finger protein 23 |
| Synonyms | hJUNE-1b, JUNE-1, MGC2941, PHD finger protein 23 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Phf23 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- PHD zinc finger
- PHD-like zinc-binding domain
- PHD finger superfamily
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Phf23 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- autophagy
- positive regulation of protein ubiquitination
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- metal ion binding