Nt5dc2 Gene Summary [Rat]
Predicted to enable 5'-nucleotidase activity. Involved in negative regulation of dopamine biosynthetic process; negative regulation of oxidoreductase activity; and negative regulation of peptidyl-serine phosphorylation. Located in cytoplasm. Orthologous to human NT5DC2 (5'-nucleotidase domain containing 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Nt5dc2 |
| Official Name | 5'-nucleotidase domain containing 2 [Source:RGD Symbol;Acc:1305524] |
| Ensembl ID | ENSRNOG00000018358 |
| Bio databases IDs | |
| Aliases | 5'-nucleotidase domain containing 2 |
| Synonyms | 2510015F01Rik, 5'-nucleotidase domain containing 2, Flj12442, RGD1305524 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Nt5dc2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- HAD superfamily (subfamily IG) hydrolase, 5'-nucleotidase
- 5' nucleotidase family
- protein binding
- Haloacid Dehalogenase-like Hydrolases
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Nt5dc2 gene, providing context for its role in the cell.
Molecular Function
What the gene product does at the molecular level
- metal ion binding
- 5'-nucleotidase activity