Nt5dc2 Gene Summary [Mouse]

Predicted to enable 5'-nucleotidase activity. Is expressed in several structures, including brain; craniocervical region bone; eye; gut gland; and urinary system. Orthologous to human NT5DC2 (5'-nucleotidase domain containing 2). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Nt5dc2
Official Name
5'-nucleotidase domain containing 2 [Source:MGI Symbol;Acc:MGI:1917271]
Ensembl ID
ENSMUSG00000071547
Bio databases IDs NCBI: 70021 Ensembl: ENSMUSG00000071547
Aliases 5'-nucleotidase domain containing 2
Synonyms 2510015F01Rik, 5'-nucleotidase domain containing 2, Flj12442, RGD1305524
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Nt5dc2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • HAD superfamily (subfamily IG) hydrolase, 5'-nucleotidase
  • 5' nucleotidase family
  • protein binding
  • Haloacid Dehalogenase-like Hydrolases

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • acute myeloid leukemia
  • osteoarthritis
  • pervasive developmental disorder
  • cataract
regulated by
regulates
  • dopamine
  • peptide

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Mitochondria

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Nt5dc2 gene, providing context for its role in the cell.

Molecular Function

What the gene product does at the molecular level
  • metal ion binding
  • 5'-nucleotidase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.