Cdk2ap2 Gene Summary [Rat]
Predicted to be involved in negative regulation of G1/S transition of mitotic cell cycle; regulation of microtubule cytoskeleton organization; and regulation of stem cell division. Predicted to be part of NuRD complex. Predicted to be active in cytoplasm; microtubule; and nucleus. Orthologous to human CDK2AP2 (cyclin dependent kinase 2 associated protein 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cdk2ap2 |
| Official Name | cyclin-dependent kinase 2 associated protein 2 [Source:RGD Symbol;Acc:1588883] |
| Ensembl ID | ENSRNOG00000018391 |
| Bio databases IDs | |
| Aliases | cyclin-dependent kinase 2 associated protein 2 |
| Synonyms | 5830466O21Rik, Al480459, cyclin-dependent kinase 2 associated protein 2, D19Ertd144e, DOC-1R, LOC683786, p14 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cdk2ap2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- microtubules
- spindle fibers
- germinal vesicles
- mitotic spindle
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Cdk2ap2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of microtubule cytoskeleton organization
- negative regulation of G1/S transition of mitotic cell cycle
- regulation of stem cell division
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- NuRD complex
- microtubule
Molecular Function
What the gene product does at the molecular level
- protein binding