Cpne6 Gene Summary [Rat]
Predicted to enable calcium-dependent phospholipid binding activity and phosphatidylserine binding activity. Predicted to be involved in cellular response to calcium ion; positive regulation of dendrite extension; and postsynaptic actin cytoskeleton organization. Predicted to be located in several cellular components, including axon; clathrin-coated endocytic vesicle; and dendrite. Predicted to be active in plasma membrane. Orthologous to human CPNE6 (copine 6). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cpne6 |
| Official Name | copine 6 [Source:RGD Symbol;Acc:1583895] |
| Ensembl ID | ENSRNOG00000018399 |
| Bio databases IDs | |
| Aliases | copine 6 |
| Synonyms | copine-6, copine VI, LOC305894 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cpne6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Copine
- phospholipid binding
- binding protein
- von Willebrand factor (vWF) type A domain
- vWFA
- calcium ion binding
- enzyme
- protein binding
- Protein kinase C conserved region 2 (CalB)
- C2 domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- Cytoplasm
- cellular membrane
- endocytotic vesicle
- axons
- dendrites
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Cpne6 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cellular response to calcium ion
- cell differentiation
Cellular Component
Where in the cell the gene product is active
- dendrite
- endosome
- extracellular vesicular exosome
- membrane
- clathrin-coated endocytic vesicle
- perikaryon
- plasma membrane
- axon
Molecular Function
What the gene product does at the molecular level
- phosphatidylserine binding
- protein binding
- calcium ion binding
- calcium-dependent phospholipid binding