Cpne6 Gene Summary [Mouse]

Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene is one of several genes that encodes a calcium-dependent protein containing two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2018]

Details

Type
Protein Coding
Official Symbol
Cpne6
Official Name
copine VI [Source:MGI Symbol;Acc:MGI:1334445]
Ensembl ID
ENSMUSG00000022212
Bio databases IDs NCBI: 12891 Ensembl: ENSMUSG00000022212
Aliases copine VI
Synonyms copine-6, copine VI, LOC305894
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cpne6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Copine
  • phospholipid binding
  • binding protein
  • von Willebrand factor (vWF) type A domain
  • vWFA
  • calcium ion binding
  • enzyme
  • protein binding
  • Protein kinase C conserved region 2 (CalB)
  • C2 domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
role in cell
  • extension
  • response by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • Cytoplasm
  • cellular membrane
  • endocytotic vesicle
  • axons
  • dendrites

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Cpne6 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cellular response to calcium ion
  • cell differentiation

Cellular Component

Where in the cell the gene product is active
  • dendrite
  • endosome
  • extracellular vesicular exosome
  • membrane
  • clathrin-coated endocytic vesicle
  • perikaryon
  • plasma membrane
  • axon

Molecular Function

What the gene product does at the molecular level
  • phosphatidylserine binding
  • protein binding
  • calcium ion binding
  • calcium-dependent phospholipid binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.