Sfi1 Gene Summary [Rat]

Predicted to enable phosphatase binding activity. Predicted to be located in centriole. Orthologous to human SFI1 (SFI1 centrin binding protein). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Sfi1
Official Name
SFI1 centrin binding protein [Source:RGD Symbol;Acc:1560636]
Ensembl ID
ENSRNOG00000018412
Bio databases IDs NCBI: 305467 Ensembl: ENSRNOG00000018412
Aliases SFI1 centrin binding protein
Synonyms C330046E03, hSfi1p, KIAA0542, PISD, PPP1R139, RGD1560636, SFI1 centrin binding protein, Sfi1 homolog, spindle assembly associated (yeast), SfiI
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Sfi1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Sfi1 repeat
  • protein binding
  • Sfi1 spindle body protein
  • phosphatase binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • non-insulin-dependent diabetes mellitus
  • age-related hearing loss
regulated by
regulates
role in cell
  • duplication in
  • duplication

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • centriole
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Sfi1 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • centriole
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • phosphatase binding
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.