Rpl18a Gene Summary [Rat]
Predicted to be a structural constituent of ribosome. Involved in response to antineoplastic agent. Located in ribosome. Part of cytosolic large ribosomal subunit. Is active in postsynaptic density. Biomarker of alcohol use disorder. Orthologous to human RPL18A (ribosomal protein L18a). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rpl18a |
| Official Name | ribosomal protein L18A [Source:RGD Symbol;Acc:1302976] |
| Ensembl ID | ENSRNOG00000018795 |
| Bio databases IDs | |
| Aliases | ribosomal protein L18A |
| Synonyms | 2510019J09RIK, 60 Ribosomal Protein L18a, eL20, L18A, Mgc72957, ribosomal protein L18A, RL18A |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Rpl18a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- structural constituent of ribosome
- protein binding
- Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A
- RNA binding
Pathways
Biological processes and signaling networks where the Rpl18a gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- ribosome
- cytosol
- nucleoli
- synapse
- postsynaptic density
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Rpl18a gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cytoplasmic translation
- translation
Cellular Component
Where in the cell the gene product is active
- cytosolic ribosome
- cytoplasm
- membrane
- cytosol
- cytosolic large ribosomal subunit
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding
- structural constituent of ribosome