Eif1b Gene Summary [Mouse]
Predicted to enable RNA binding activity; ribosomal small subunit binding activity; and translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be part of eukaryotic 43S preinitiation complex. Is expressed in several structures, including brain; cardiovascular system; genitourinary system; gut; and hemolymphoid system gland. Orthologous to human EIF1B (eukaryotic translation initiation factor 1B). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Eif1b |
| Official Name | eukaryotic translation initiation factor 1B [Source:MGI Symbol;Acc:MGI:1916219] |
| Ensembl ID | ENSMUSG00000006941 |
| Bio databases IDs | |
| Aliases | eukaryotic translation initiation factor 1B |
| Synonyms | 1500010M16Rik, 3110001N14Rik, eukaryotic translation initiation factor 1B, GC20, RGD1309241 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Eif1b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Translation initiation factor SUI1
- protein binding
- translation regulator
- Eukaryotic initiation factor 1 and related proteins
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Eif1b gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- translational initiation
- regulation of translational initiation
Cellular Component
Where in the cell the gene product is active
- eukaryotic 43S preinitiation complex
Molecular Function
What the gene product does at the molecular level
- translation initiation factor activity
- protein binding
- RNA binding
- ribosomal small subunit binding