Mtg1 Gene Summary [Rat]

Predicted to enable GTPase activity. Predicted to be involved in several processes, including mitochondrial large ribosomal subunit assembly; regulation of mitochondrial translation; and regulation of respiratory system process. Predicted to be located in mitochondrial inner membrane; mitochondrial ribosome; and nucleoplasm. Predicted to be active in mitochondrial matrix. Orthologous to human MTG1 (mitochondrial ribosome associated GTPase 1). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Mtg1
Official Name
mitochondrial ribosome-associated GTPase 1 [Source:RGD Symbol;Acc:6497155]
Ensembl ID
ENSRNOG00000018860
Bio databases IDs NCBI: 100910751 Ensembl: ENSRNOG00000018860
Aliases mitochondrial ribosome-associated GTPase 1
Synonyms Gm169, GTP, GTPBP7, mitochondrial ribosome-associated GTPase 1
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Mtg1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • ribosome biogenesis GTP-binding protein YlqF
  • GTPase
  • enzyme
  • protein binding
  • Circularly permuted YlqF-related GTPases

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • systemic lupus erythematosus
  • insulin-dependent diabetes mellitus
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Mitochondria
  • mitochondrial matrix
  • mitochondrial inner membrane
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Mtg1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • regulation of respiratory system process
  • mitochondrial translation
  • regulation of mitochondrial translation

Cellular Component

Where in the cell the gene product is active
  • mitochondrial matrix
  • mitochondrion
  • mitochondrial ribosome
  • mitochondrial inner membrane
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • GTP binding
  • protein binding
  • GTPase activity

Gene-Specific Assays for Results You Can Trust

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