Tm6sf1 Gene Summary [Rat]

Predicted to be active in lysosomal membrane. Orthologous to human TM6SF1 (transmembrane 6 superfamily member 1). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Tm6sf1
Official Name
transmembrane 6 superfamily member 1 [Source:RGD Symbol;Acc:1307978]
Ensembl ID
ENSRNOG00000019662
Bio databases IDs NCBI: 361600 Ensembl: ENSRNOG00000019662
Aliases transmembrane 6 superfamily member 1
Synonyms AI428514, C630016D09Rik, transmembrane 6 superfamily member 1
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Tm6sf1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • transmembrane 6 superfamily member 1, member 2, and similar proteins
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • X-linked immunodeficiency with magnesium defect, Epstein-Barr virus infection and neoplasia
regulated by
  • T lymphocytes
  • calcitriol
  • hematopoietic progenitor cells
  • megakaryocytes
  • MYCN
  • PPRC1
  • carbonyl cyanide m-chlorophenyl hydrazone

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cellular membrane
  • lysosome membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Tm6sf1 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • lysosomal membrane

Gene-Specific Assays for Results You Can Trust

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