Pprc1 Gene Summary [Rat]
Predicted to enable transcription coactivator activity. Predicted to be involved in energy homeostasis and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Orthologous to human PPRC1 (PPARG related coactivator 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Pprc1 |
| Official Name | PPARG related coactivator 1 [Source:RGD Symbol;Acc:1309688] |
| Ensembl ID | ENSRNOG00000018561 |
| Bio databases IDs | |
| Aliases | PPARG related coactivator 1 |
| Synonyms | A930018M19, BC013720, LOC105378459, mKIAA0595, Peroxisome proliferative activated receptor gamma coactivator-related 1, peroxisome proliferative activated receptor, gamma, coactivator-related 1, Peroxisome proliferative activated receptor γ coactivator-related 1, peroxisome proliferative activated receptor, γ, coactivator-related 1, PPARG related coactivator 1, PRC |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Pprc1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- RNA recognition motif (RRM) superfamily
- transcription regulator
- LXXLL motif
- RNA recognition motif
Pathways
Biological processes and signaling networks where the Pprc1 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- lymphoma
- lymphomagenesis
- Huntington disease
role in cell
- proliferation
- binding in
- expression in
- mass
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Pprc1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of sequence-specific DNA binding transcription factor activity
- positive regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- nucleus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- RNA binding
- ligand-dependent nuclear receptor transcription coactivator activity
- transcription factor binding