Gdap2 Gene Summary [Rat]
Predicted to act upstream of or within response to retinoic acid. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 27. Orthologous to human GDAP2 (ganglioside induced differentiation associated protein 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Gdap2 |
| Official Name | ganglioside-induced differentiation-associated-protein 2 [Source:RGD Symbol;Acc:1306050] |
| Ensembl ID | ENSRNOG00000019754 |
| Bio databases IDs | |
| Aliases | ganglioside-induced differentiation-associated-protein 2 |
| Synonyms | D3Ertd801e, ganglioside-induced differentiation-associated-protein 2, MACROD3, SCAR27 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Gdap2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- macro domain
- Domain in homologues of a S
- Divergent CRAL/TRIO domain
- macrodomain superfamily
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Gdap2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- response to retinoic acid
Cellular Component
Where in the cell the gene product is active
- lysosomal membrane
Molecular Function
What the gene product does at the molecular level
- protein binding