Samd4b Gene Summary [Rat]

Enables RNA binding activity. Predicted to be involved in nuclear-transcribed mRNA poly(A) tail shortening. Predicted to act upstream of or within cerebellar neuron development. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Nonsense Mediated Decay
Official Symbol
Samd4b
Official Name
sterile alpha motif domain containing 4B [Source:RGD Symbol;Acc:1305597]
Ensembl ID
ENSRNOG00000019831
Bio databases IDs NCBI: 308473 Ensembl: ENSRNOG00000019831
Aliases sterile alpha motif domain containing 4B
Synonyms FLJ10211, RGD1305597, Smaug2, SMGB, sterile alpha motif domain containing 4B, sterile α motif domain containing 4B
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Samd4b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Sterile alpha motif
  • mRNA binding
  • SAM (Sterile alpha motif )
  • SAM domain (Sterile alpha motif)
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
  • BGA002
regulates
role in cell
  • neurogenesis
  • depletion

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Nucleus
  • cytosol
  • P-body granule

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Samd4b gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • negative regulation of translation
  • nuclear-transcribed mRNA poly(A) tail shortening

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasmic mRNA processing body
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • RNA binding
  • translation repressor activity
  • mRNA binding

Gene-Specific Assays for Results You Can Trust

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