SAMD4B Gene Summary [Human]
Enables RNA binding activity. Predicted to be involved in nuclear-transcribed mRNA poly(A) tail shortening. Predicted to act upstream of or within cerebellar neuron development. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | SAMD4B |
| Official Name | sterile alpha motif domain containing 4B [Source:HGNC Symbol;Acc:HGNC:25492] |
| Ensembl ID | ENSG00000179134 |
| Bio databases IDs | |
| Aliases | sterile alpha motif domain containing 4B, smaug homolog B (Drosophila) |
| Synonyms | FLJ10211, RGD1305597, Smaug2, SMGB, sterile alpha motif domain containing 4B, sterile α motif domain containing 4B |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SAMD4B often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Sterile alpha motif
- mRNA binding
- SAM (Sterile alpha motif )
- SAM domain (Sterile alpha motif)
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- cytosol
- P-body granule
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SAMD4B gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of translation
- nuclear-transcribed mRNA poly(A) tail shortening
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasmic mRNA processing body
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding
- translation repressor activity
- mRNA binding