Cope Gene Summary [Rat]
Predicted to enable structural molecule activity. Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport and intra-Golgi vesicle-mediated transport. Predicted to act upstream of or within protein localization to axon. Predicted to be located in COPI-coated vesicle; Golgi apparatus; and nucleoplasm. Predicted to be part of COPI vesicle coat. Orthologous to human COPE (COPI coat complex subunit epsilon). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cope |
| Official Name | coatomer protein complex, subunit epsilon [Source:RGD Symbol;Acc:1306785] |
| Ensembl ID | ENSRNOG00000020178 |
| Bio databases IDs | |
| Aliases | coatomer protein complex, subunit epsilon |
| Synonyms | 1110005D17Rik, coatomer protein complex, subunit epsilon, coatomer protein complex, subunit ε, Cope1, Cope predicted, COPI coat complex subunit epsilon, COPI coat complex subunit ε, epsilon-COP, ε-COP |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cope often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Coatomer epsilon subunit
- protein binding
- transporter
Pathways
Biological processes and signaling networks where the Cope gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- endoplasmic reticulum mitochondria contact site
- Nucleus
- Golgi Apparatus
- cytosol
- endoplasmic reticulum membrane
- Golgi membrane
- nucleoplasm
- transport vesicles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Cope gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- ER to Golgi vesicle-mediated transport
- retrograde vesicle-mediated transport, Golgi to ER
- protein transport
- intra-Golgi vesicle-mediated transport
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- cytosol
- Golgi membrane
- Golgi apparatus
- transport vesicle
- COPI vesicle coat
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- structural molecule activity