LOC102549471 Gene Summary [Rat]

Predicted to enable damaged DNA binding activity. Predicted to be involved in single strand break repair. Predicted to be located in chromosome and nucleolus. Orthologous to human XNDC1N (XRCC1 N-terminal domain containing 1, N-terminal like). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
LOC102549471
Official Name
short transient receptor potential channel 2-like [Source:RGD Symbol;Acc:7692537]
Ensembl ID
ENSRNOG00000020188
Bio databases IDs NCBI: 64573 Ensembl: ENSRNOG00000020188
Aliases short transient receptor potential channel 2-like
Synonyms 3010009O07RIK, AI115608, mTrp2, smTRPC2, transient receptor potential cation channel subfamily C member 2, transient receptor potential cation channel, subfamily C, member 2, trp2, TRPC2a, TRPC2b, Trrp2
Species
Rat, Rattus norvegicus
OrthologiesMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Loc102549471 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • binding protein
  • Ion transport protein
  • diacylglycerol binding
  • Ankyrin repeats (3 copies)
  • Transient receptor ion channel II
  • transient-receptor-potential calcium channel protein
  • store-operated calcium channel
  • cytosolic tail domain
  • protein binding
  • ion channel
  • Transient Receptor Potential channel, Vanilloid subfamily (TRPV)
  • Polycystin cation channel

Pathways

Biological processes and signaling networks where the Loc102549471 gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
regulates
  • ERK1/2
  • cyclic AMP
  • Ca2+
  • TSHR
  • TG
regulated by
  • Gstp1 (includes others)
  • ASIP
  • Ca2+
  • phenylephrine
  • carbamylcholine
  • diacylglycerol
  • tetradecanoylphorbol acetate
  • thapsigargin
disease
  • cancer
  • melanoma cancer
role in cell
  • phosphorylation in
  • expression in
  • production in
  • function
  • abnormal morphology
  • elevation in
  • innervation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • endomembrane system
  • cellular membrane
  • microvilli
  • perikaryon
  • dendrites
  • dendritic knobs

Gene-Specific Assays for Results You Can Trust

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