Enkur Gene Summary [Rat]

Predicted to enable calmodulin binding activity. Predicted to act upstream of or within establishment of left/right asymmetry and flagellated sperm motility. Predicted to be located in 9+0 motile cilium and sperm principal piece. Predicted to be active in acrosomal vesicle; axonemal B tubule inner sheath; and sperm flagellum. Orthologous to human ENKUR (enkurin, TRPC channel interacting protein). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Enkur
Official Name
enkurin, TRPC channel interacting protein [Source:RGD Symbol;Acc:1309839]
Ensembl ID
ENSRNOG00000018631
Bio databases IDs NCBI: 291354 Ensembl: ENSRNOG00000018631
Aliases enkurin, TRPC channel interacting protein
Synonyms 4933434I06Rik, C10orf63, CFAP106, enkurin, TRPC channel interacting protein, RGD1309839
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Enkur often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Calmodulin-binding
  • calmodulin binding
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • dextrocardia
  • organismal death
  • situs ambiguus
  • situs inversus totalis
regulated by
regulates
role in cell
  • expression in
  • proliferation
  • invasion by
  • migration
  • motility
  • function
  • sorafenib resistance

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • motile cilia
  • flagella
  • axonemes
  • sperm tail
  • acrosome

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Enkur gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • sperm motility

Cellular Component

Where in the cell the gene product is active
  • axonemal microtubule
  • acrosomal vesicle
  • sperm principal piece

Molecular Function

What the gene product does at the molecular level
  • calmodulin binding
  • protein binding
  • SH3 domain binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.