Slc25a24 Gene Summary [Rat]

Predicted to enable ADP:phosphate antiporter activity; ATP:phosphate antiporter activity; and calcium ion binding activity. Predicted to be involved in cellular response to calcium ion; cellular response to oxidative stress; and purine ribonucleotide transport. Predicted to be located in membrane and mitochondrion. Orthologous to human SLC25A24 (solute carrier family 25 member 24). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Slc25a24
Official Name
solute carrier family 25 member 24 [Source:RGD Symbol;Acc:1311982]
Ensembl ID
ENSRNOG00000020470
Bio databases IDs NCBI: 310791 Ensembl: ENSRNOG00000020470
Aliases solute carrier family 25 member 24
Synonyms 2610016M12RIK, APC1, DKFZP586G0123, MITOCHONDRIAL CALCIUM TRANSPROTER, SCAMC-1, solute carrier family 25 member 24
Species
Rat, Rattus norvegicus
OrthologiesHuman

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Slc25a24 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • EF-hand, calcium binding motif
  • Dockerin type I domain
  • EF-hand domain pair
  • Mitochondrial carrier protein
  • calcium ion binding
  • EFh
  • EFh_PI-PLC
  • ADP transporter
  • ATP transporter
  • EF-hand domain
  • adenine nucleotide transporter
  • EF hand
  • EF-hand, calcium binding motif, found in parvalbumin-like EF-hand family
  • Eps15 homology domain
  • transporter
  • organophosphate:inorganic phosphate antiporter
  • Dockerin repeat domains and domains resembling dockerin repeats

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • Fontaine progeroid syndrome
  • chronic periodontal disease
regulated by
regulates
role in cell
  • apoptosis
  • transport
  • response by
  • transport in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cellular membrane
  • Mitochondria

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Slc25a24 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cellular response to calcium ion
  • mitochondrial transport
  • cellular response to oxidative stress
  • ATP transport
  • adenine nucleotide transport
  • ADP transport

Cellular Component

Where in the cell the gene product is active
  • membrane
  • mitochondrion
  • mitochondrial inner membrane

Molecular Function

What the gene product does at the molecular level
  • adenine nucleotide transmembrane transporter activity
  • calcium ion binding
  • ATP transmembrane transporter activity

Gene-Specific Assays for Results You Can Trust

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