Pds5a Gene Summary [Rat]
Predicted to be involved in DNA repair; mitotic sister chromatid cohesion; and negative regulation of DNA replication. Predicted to act upstream of or within several processes, including lens development in camera-type eye; neuroblast migration; and roof of mouth development. Predicted to be located in nucleoplasm and plasma membrane. Predicted to be active in chromatin and nucleus. Orthologous to human PDS5A (PDS5 cohesin associated factor A). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Pds5a |
| Official Name | PDS5 cohesin associated factor A [Source:RGD Symbol;Acc:1307094] |
| Ensembl ID | ENSRNOG00000002541 |
| Bio databases IDs | |
| Aliases | PDS5 cohesin associated factor A |
| Synonyms | 9030416H16Rik, B230308N11Rik, E230024D05Rik, KIAA0648, PDS5, PDS5 cohesin associated factor A, PIG54, RGD1307094, SCC-112 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Pds5a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- Sister chromatid cohesion protein PDS5 protein
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Plasma Membrane
- cytosol
- chromosome
- nucleoplasm
- centromeres
- chromatin
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Pds5a gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell division
- DNA repair
- mitotic sister chromatid cohesion
- negative regulation of DNA replication
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytosol
- chromosome
- chromosome, centromeric region
- chromatin
- plasma membrane
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding